Both are hemp extracts. An isolate is a cheaper concentrated extract that contains 99% CBD only, the Full Spectrum oil are typically 75-80% CBD with supporting terpenes, amino acids, and other nutrients that contribute to the entourage effect. With a full spectrum product the various nutrients support other elements in having the desired effect on the body. We believe that nature has a lot of wisdom so all out products have the Full Spectrum of supportive elements. Full spectrum oils, while being costlier to produce are loved for their wholistic benefits.